All Biomarkers

    Stool Bile Acids (Total)

    Gut & Microbiome
    Metabolites
    µmol/g

    Total stool bile acids measure how much bile acid is being excreted in the stool, reflecting the balance of bile production, reabsorption, and microbial processing. A preventive practice uses it because excess can drive bile acid diarrhea, while low output can signal fat malabsorption or ileal disease.

    What It Measures

    Total fecal bile acid output.

    Optimal vs. Lab Range

    Longevity Optimal
    Within reference

    Target range for optimal health and longevity based on research.

    Standard Lab
    Lab-specific

    Population-based reference range from standard labs.

    Why It Matters

    Excess → bile acid diarrhea; low → fat malabsorption / ileal disease.

    When Low

    Low → fat malabsorption.

    When Optimal

    Within range → normal recycling.

    When High

    Elevated → bile acid diarrhea pattern.

    How to Optimize

    GI workup; bile acid sequestrants if indicated; soluble fiber.

    Key Interventions & Linked Compounds

    Moderate (6/10)

    Key Interventions

    Cholestyramine (Rx)
    psyllium
    low-fat trial.

    Linked Compounds & Supplements

    Cholestyramine
    psyllium.

    Curated from clinical literature. Individual results vary; consult a qualified clinician before changing a protocol.

    Ordering Notes

    Specimen

    Serum or plasma (venous draw)

    Patient prep

    No fasting required. Maintain usual diet and medications unless advised.

    Recommended cadence

    Re-test every 3–6 months when actively optimizing; annually for monitoring.

    Reporting unit

    µmol/g

    Pre-analytic notes

    Standardize draw time of day, hydration, and recent exercise. Note any acute illness, supplements, or hormonal therapies on the requisition.

    Recommended Follow-Up Actions

    1. 1

      Confirm the result is reliable

      Repeat abnormal values before acting — preferably from the same lab, same time of day, and under consistent prep. Rule out acute illness, recent intense exercise, or medication effects that can shift Stool Bile Acids (Total).

    2. 2

      Compare against optimal, not just lab range

      Use the optimal window above as the target. Lab "normal" is built from the general population and often misses early dysfunction.

    3. 3

      Pair with related markers

      Order a complementary panel covering metabolic, inflammatory, and hormonal context to interpret this marker properly.

    4. 4

      Discuss interventions with a clinician

      Use the interpretation guidance above to frame the conversation. Bring trends, not just one datapoint, to your visit.

    5. 5

      Re-test on a defined cadence

      If a change is implemented, re-measure in 8–12 weeks for fast-moving markers, or 3–6 months for slower ones, to confirm response before escalating.

    PHS
    671
    / 1000
    T3
    Longevity Operator

    Sample member

    Longevity Operator

    The Peak Human Score · PHS v1

    One number for your longevity journey.

    FICO for credit. PHS for longevity. Eight biological domains collapsed into one provable score — intuitive at a glance, rigorous underneath.

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    • Gut
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