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    PAPER GDF15-Cohort Study

    Association of DNA methylation-predicted growth differentiation factor 15 with all-cause mortality among older adults (NHANES 1999-2002)

    Prospective NHANES analysis: DNA methylation-predicted GDF-15 was an independent predictor of all-cause mortality in older US adults, with a nonlinear dose-response.

    Evidence

    6/10

    Moderate Evidence

    Sample

    —

    subjects

    Duration

    —

    study period

    Journal

    —

    02

    Key Findings

    1. 01

      Epigenetically predicted GDF-15 independently predicted all-cause mortality

    2. 02

      Nonlinear dose-response relationship

    03

    Structured Methods

    Study Design
    Cohort Study
    Sample Size
    Not reported
    Study Duration
    Not reported
    Methodology
    Not reported
    Limitations
    Not reported
    04

    Citations & References

    Cite this paper

    Unknown authors (n.d.). Association of DNA methylation-predicted growth differentiation factor 15 with all-cause mortality among older adults (NHANES 1999-2002).

    Source

    Publisher

    05

    Indexing

    Topics

    mortalityepigeneticsbiological aging

    Biomarkers

    GDF-15
    PHS
    671
    / 1000
    T3
    Longevity Operator

    Sample member

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