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    PAPER GFAP-PCohort Study2021

    Plasma GFAP is an early marker of amyloid-beta but not tau pathology in Alzheimer's disease

    In the BioFINDER-2 cohort, plasma GFAP increased early and tracked amyloid-beta rather than tau, indicating astrocyte reactivity to amyloid.

    Evidence

    7/10

    Moderate Evidence

    Sample

    —

    subjects

    Duration

    —

    study period

    Journal

    Brain

    Nov 2021

    02

    Key Findings

    1. 01

      Plasma GFAP rises early and tracks amyloid-beta rather than tau

    2. 02

      Supports GFAP as a marker of amyloid-associated astrocyte reactivity

    03

    Structured Methods

    Study Design
    Cohort Study
    Sample Size
    Not reported
    Study Duration
    Not reported
    Methodology
    Not reported
    Limitations
    Not reported
    04

    Citations & References

    Cite this paper

    Unknown authors (2021). Plasma GFAP is an early marker of amyloid-beta but not tau pathology in Alzheimer's disease. Brain.

    Source

    Publisher

    Journal

    Brain

    05

    Indexing

    Topics

    Alzheimer'samyloid

    Biomarkers

    GFAP
    PHS
    671
    / 1000
    T3
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