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    Supplement

    BoronNew

    Supplement
    Minerals
    4/10 Evidence

    Trace mineral cofactor influencing steroid hormone metabolism, bone mineralization, and inflammatory markers — an overlooked lever previously missing from a Minerals category covering Magnesium, Lithium, and Zinc+Copper.

    Mechanism of Action

    Modulates enzymes involved in steroidogenesis and vitamin D activation, reduces SHBG binding affinity and urinary calcium/magnesium loss, and downregulates hs-CRP and TNF-α inflammatory signaling.

    Dosing Protocol

    Recommended

    3mg (as boron citrate or glycinate)

    Standard starting dose based on research

    Therapeutic Range

    3

    Minimum

    to

    6

    Maximum

    mg (as boron citrate or glycinate)

    With food

    Cycling Protocol

    Typically continuous at 3-6mg/day; avoid sustained long-term use above 10-20mg/day

    Dosages are general guidelines. Individual requirements vary based on body weight, health status, and specific goals. Start with lower doses and adjust based on response.

    Benefits

    Primary Benefits

    • Bone mineral density support
    • Free testosterone/estradiol modulation
    • Reduced systemic inflammation markers

    Secondary Benefits

    Joint comfort
    Cognitive/psychomotor performance (limited evidence)

    Safety Information

    Contraindications

    Do not use if any of the following apply:

    • •Pregnancy/breastfeeding
    • •Hormone-sensitive conditions

    Drug/Supplement Interactions

    May interact with the following. Consult a healthcare provider before combining:

    Additive effect with other hormone-modulating supplements (e.g. DHEA, Tongkat Ali)

    Potential Side Effects

    Some users may experience:

    GI upset at high doses
    Headache (rare)

    This is not a complete list of interactions or side effects. Individual responses vary. Always start with the lowest effective dose and monitor your response. Report any adverse effects to your healthcare provider.

    Quality Markers

    Look for these specific quality indicators when sourcing this compound:

    • Chelated form (citrate/glycinate) preferred over borax/boric acid
    • Third-party tested

    Trusted Certifications

    NSF Certified
    USP Verified
    GMP Certified
    ConsumerLab Approved

    Note: Supplement quality varies dramatically between brands. Cheap supplements often contain fillers, incorrect doses, or contaminants. Investing in quality products from reputable manufacturers is essential for safety and efficacy.

    Evidence Profile

    Evidence Score

    4/10

    Emerging/Anecdotal

    Limited clinical data, primarily mechanistic studies or user reports

    Classification:
    Emerging/Moderate Evidence

    Evidence Scale

    8-10

    Strong

    5-7

    Moderate

    1-4

    Emerging

    PHS
    671
    / 1000
    T3
    Longevity Operator

    Sample member

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