Glutathione (Liposomal)New
The body's master antioxidant, delivered in a liposomal capsule to bypass the gut degradation that limits plain oral glutathione. Supports detoxification, immune function, and cellular redox balance.
Mechanism of Action
Glutathione (GSH) neutralizes reactive oxygen species directly and serves as the cofactor for glutathione peroxidase and glutathione-S-transferase, the primary Phase II liver detoxification enzymes. Oral GSH is largely broken down by gut peptidases into its constituent amino acids before reaching circulation; liposomal encapsulation protects the tripeptide through the GI tract and ferries it across the intestinal membrane intact, raising plasma concentrations well above plain oral forms.
Dosing Protocol
500mg once or twice dailymg
Standard starting dose based on research
Therapeutic Range
250
Minimum
1000
Maximum
On an empty stomach, morning
Dosages are general guidelines. Individual requirements vary based on body weight, health status, and specific goals. Start with lower doses and adjust based on response.
Benefits
Primary Benefits
- Antioxidant defense
- Liver detoxification support
- Immune function
- Improved cellular delivery vs. plain oral GSH
Secondary Benefits
Safety Information
Contraindications
Do not use if any of the following apply:
- •Active chemotherapy (without oncologist approval)
- •Asthma (rare bronchospasm reports with inhaled/nebulized forms, not oral)
Drug/Supplement Interactions
May interact with the following. Consult a healthcare provider before combining:
Potential Side Effects
Some users may experience:
This is not a complete list of interactions or side effects. Individual responses vary. Always start with the lowest effective dose and monitor your response. Report any adverse effects to your healthcare provider.
Quality Markers
Look for these specific quality indicators when sourcing this compound:
- Liposomal or micellar encapsulation (not plain reduced glutathione)
- Third-party tested for oxidation (GSSG:GSH ratio)
- Non-GMO sunflower or soy lecithin liposomes
Trusted Certifications
Note: Supplement quality varies dramatically between brands. Cheap supplements often contain fillers, incorrect doses, or contaminants. Investing in quality products from reputable manufacturers is essential for safety and efficacy.
Evidence Profile
Evidence Score
5/10
Moderate Evidence
Some clinical trials with positive results, emerging research
Evidence Scale
8-10
Strong
5-7
Moderate
1-4
Emerging
Sample member
Longevity Operator
One number for your longevity journey.
FICO for credit. PHS for longevity. Eight biological domains collapsed into one provable score — intuitive at a glance, rigorous underneath.
- Metabolic
- Hormonal
- Cardiovascular
- Brain / Cognitive
- Sleep
- Musculoskeletal
- Gut
- Immunity / Inflammation