peakhuman@intel:~/database/feeds/patents/p-001$
    back
    ▸ filing :: US 11,938,162★ featured·USPTO·granted

    Senolytic combination therapy targeting BCL-XL and FOXO4 pathways

    Unity Biotechnology · published 2025-09-03 · filed 2022-04-12

    patent_no
    US 11,938,162
    classification
    A61K 31/4196
    category
    senolytics
    office
    USPTO

    ▸ inventors

    N. David, M. Laberge

    ▸ abstract

    A pharmaceutical composition combining a small-molecule BCL-XL inhibitor with a FOXO4-DRI peptide for the selective clearance of senescent cells in age-related tissue dysfunction, with reduced thrombocytopenia profile.

    ▸ topics

    #senescence#BCL-XL#FOXO4#combination therapy

    ▸ source links

    PHS
    671
    / 1000
    T3
    Longevity Operator

    Sample member

    Longevity Operator

    The Peak Human Score · PHS v1

    One number for your longevity journey.

    FICO for credit. PHS for longevity. Eight biological domains collapsed into one provable score — intuitive at a glance, rigorous underneath.

    • Metabolic
    • Hormonal
    • Cardiovascular
    • Brain / Cognitive
    • Sleep
    • Musculoskeletal
    • Gut
    • Immunity / Inflammation