●peakhuman@intel:~/database/feeds/patents/p-002$
▸ filing :: WO 2025/041337★ featured·WIPO·published
Engineered klotho variants with extended half-life for cognitive aging
Klotho Neurosciences · published 2025-08-21 · filed 2024-02-20
patent_no
WO 2025/041337
classification
C07K 14/47
category
peptides
office
WIPO
▸ inventors
J. Park, S. Velasquez
▸ abstract
Recombinant α-klotho fusion proteins fused to an Fc domain demonstrating 6-fold serum half-life extension and improved blood-brain barrier penetrance in non-human primate models.
▸ topics
#klotho#cognition#fusion protein#BBB
▸ source links
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