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    Supplement

    Vitamin D3 + K2

    Supplement
    Vitamins
    9/10 Evidence

    Synergistic combination ensuring proper calcium metabolism—D3 increases calcium absorption while K2 directs it to bones instead of arteries.

    Mechanism of Action

    D3 acts as a hormone precursor regulating 1000+ genes. K2 activates osteocalcin (bone) and matrix GLA protein (arterial protection).

    Dosing Protocol

    Recommended

    5000 IU D3 / 200mcg K2-MK7IU/mcg

    Standard starting dose based on research

    Therapeutic Range

    2000/100

    Minimum

    to

    10000/300

    Maximum

    IU/mcg

    Morning with fat-containing meal

    Dosages are general guidelines. Individual requirements vary based on body weight, health status, and specific goals. Start with lower doses and adjust based on response.

    Benefits

    Primary Benefits

    • Bone health
    • Immune function
    • Cardiovascular protection
    • Mood support

    Secondary Benefits

    Cancer risk reduction
    Autoimmune modulation
    Muscle function

    Safety Information

    Contraindications

    Do not use if any of the following apply:

    • Hypercalcemia
    • Warfarin (K2 component)
    • Granulomatous disease

    Potential Side Effects

    Some users may experience:

    Rare at recommended doses
    Possible hypercalcemia if excessive

    This is not a complete list of interactions or side effects. Individual responses vary. Always start with the lowest effective dose and monitor your response. Report any adverse effects to your healthcare provider.

    Quality Markers

    Look for these specific quality indicators when sourcing this compound:

    • D3 cholecalciferol form
    • K2 as MK-7
    • Third-party verified

    Trusted Certifications

    NSF Certified
    USP Verified
    GMP Certified
    ConsumerLab Approved

    Note: Supplement quality varies dramatically between brands. Cheap supplements often contain fillers, incorrect doses, or contaminants. Investing in quality products from reputable manufacturers is essential for safety and efficacy.

    Evidence Profile

    Evidence Score

    9/10

    Strong Evidence

    Multiple high-quality RCTs, meta-analyses, or consistent mechanistic data

    Classification:
    Strong Evidence

    Evidence Scale

    8-10

    Strong

    5-7

    Moderate

    1-4

    Emerging

    PHS
    671
    / 1000
    T3
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